The 2025 NFL season is well underway, and as we hit the midpoint of October, the race for Super Bowl LX—set to take place on February 8, 2026, at Levi's Stadium in Santa Clara, California—is heating up. While the defending champion Philadelphia Eagles started strong, unexpected twists like injuries and upsets have shuffled the deck. Teams like the Buffalo Bills and Kansas City Chiefs have emerged as frontrunners, but the NFC is wide open with powerhouses like the Detroit Lions and Green Bay Packers making noise. Based on current futures odds from leading sportsbooks like BetMGM, here's a breakdown of the top contenders and their chances to hoist the Lombardi Trophy. These odds reflect the landscape as of October 19, 2025, and can fluctuate with each week's results.
Top Favorites to Win Super Bowl LX
The Buffalo Bills hold the slight edge right now, buoyed by a solid 4-2 start despite a recent sloppy loss. Their high-powered offense, led by Josh Allen, makes them a perennial threat in the AFC. Close behind are the Chiefs, who, despite a middling 3-3 record, benefit from Patrick Mahomes' magic and a proven track record in big games. In the NFC, the Lions and Packers are surging, with Detroit's balanced attack and Green Bay's young talent turning heads.
Here's a table of the top 10 teams with the best odds (from BetMGM, unless noted otherwise):
| Team | Odds | Key Notes |
|---|---|---|
| Buffalo Bills | +600 | Favorites after a strong start, but need to clean up turnovers. |
| Kansas City Chiefs | +650 | Defending multiple titles; Mahomes keeps them in every conversation. |
| Detroit Lions | +750 | NFC North leaders with a potent offense and improving defense. |
| Green Bay Packers | +800 | Jordan Love's emergence has them as dark horses. |
| Philadelphia Eagles | +1000 | Defending champs, but injuries have hampered their title defense. |
| Indianapolis Colts | +1700 | Rising after a hot streak; Anthony Richardson is key. |
| Tampa Bay Buccaneers | +1800 | Baker Mayfield's revival has them competitive in the NFC South. |
| Denver Broncos | +1800 | Bo Nix and a stout defense make them sleepers. |
| Baltimore Ravens | +2500 | Struggling at 1-5 due to injuries, but Lamar Jackson could turn it around. |
| Seattle Seahawks | +3500 | Improved odds after recent wins; Geno Smith is clicking. |
These odds represent value bets for futures, but remember, the NFL is unpredictable—last season's surprises like the Eagles' run prove anything can happen. For instance, the Ravens have seen their odds worsen from +2000 to +2500 amid a rough start, while teams like the Colts have improved from +2200 to +1700 thanks to unexpected victories.
Sleepers and Long Shots
Beyond the top tier, keep an eye on teams like the San Francisco 49ers (+1000 in some books) and Houston Texans (+1200), who could rebound with key players returning from injury. On the longer end, the Jacksonville Jaguars sit at +5000 after slipping from +2500, reflecting their inconsistent play. If you're new to betting or looking for an edge, the Fanatics Sportsbook promo code is a good choice for a welcome offer to secure before you start betting futures.
What Factors Influence These Odds?
Odds are shaped by team performance, injuries, and schedule strength. For example, the Chiefs' relatively short odds despite their record stem from their championship pedigree— they've won multiple recent Super Bowls. In contrast, the Ravens' defensive woes and Lamar Jackson's hamstring issue have pushed them down. As we head into Week 7, matchups like Bills vs. Titans and Chiefs vs. 49ers could cause shifts. Bettors should monitor injury reports and use tools like implied probability (e.g., +600 implies about 14.3% chance) to gauge value.
In summary, the Bills and Chiefs lead the pack, but the parity this season means no team is a lock. With over half the season left, these odds will evolve—stay tuned for updates as the playoff picture clarifies.
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