The Pittsburgh Steelers have been dealt a setback ahead of the 2025 NFL season as rookie defensive tackle Derrick Harmon suffered an MCL sprain during the preseason finale against the Carolina Panthers. The injury, confirmed by NFL Network’s Ian Rapoport, is expected to sideline Harmon for about a month, with the possibility that he may start the season on injured reserve.
Harmon, the Steelers’ first-round pick (21st overall) out of Oregon, sustained the injury in the first half of the game and was carted off the field. Fortunately, the diagnosis was not as severe as initially feared, ruling out a season-ending scenario. Head coach Mike Tomlin has described the injury as “week-to-week,” offering hope that Harmon could return as early as Week 2 or 3. His absence, however, will be felt during the Steelers’ opening game against the New York Jets on September 7.
Through the preseason, Harmon showed promising signs, participating in 70 defensive snaps across three games. His impact was solid, with four pressures and a sack leading to an overall defensive grade of 65.1 from Pro Football Focus. His presence on the defensive line is already significant given his ability to disrupt offenses both in pass rush and run defense.
The Steelers will likely rely more heavily on rookie fifth-round pick Yahya Black and depth defenders like Logan Lee, Daniel Ekuale, and Isaiahh Loudermilk in Harmon's absence. Black, in particular, impressed in the Panthers game, tallying two sacks and making a case for increased playing time.
Derrick Harmon’s injury is a considerable blow given the high expectations set for him. A transfer from Michigan State to Oregon, Harmon earned second-team All-Big Ten honors last season and was recognized as a second-team All-American. The Steelers envisioned him as a key piece of their defensive front, set to shore up the defensive tackle spot alongside veterans like Cameron Heyward and Keeanu Benton.
Steelers head coach Mike Tomlin acknowledged the challenge but expressed confidence in the team’s depth. “We’ve got capable players ready to step up while Derrick heals. The season is long, and we’ll be prepared to adjust as needed,” Tomlin said. “Derrick is a competitor with an incredible work ethic. We expect him back soon and stronger.”
As the Steelers face a demanding schedule, starting the season without a first-round talent like Harmon will test their run defense and overall defensive schemes. The team is relying on its defensive culture and veteran leadership to maintain balance.
Harmon himself has been optimistic about his recovery. He disclosed that he initially feared a more significant injury, but MRI results eased his concerns. He does not require surgery and plans to approach rehab aggressively to return as soon as possible. “I’m attacking this rehab. I want to be out there with the guys,” Harmon said.
While the injury forces an early season adjustment, the Steelers remain well-positioned with a solid defensive core. The hope is that Harmon’s robust recovery plan and the team's depth will cushion the blow and keep Pittsburgh competitive in the AFC North.
In summary, Derrick Harmon’s MCL sprain is a setback for a promising rookie season, but it is not a season-defining injury. The Steelers’ ability to adapt and integrate other players during his absence will be crucial as they aim to defend their divisional title and make a deep playoff run.

